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The Endocannabinoid System

The endocannabinoid system is the name for a series of cell receptors in humans that respond to cannabinoids. CB1 and CB2 receptors are crucial elements of the endocannabinoid system that are known to respond to endocannabinoids.

 CB1 Receptors

CB2 Receptors

CB1 receptors are primarily located on nerve cells in the brain and spinal cord, but are also found in peripheral organs and tissues.

In the brain, CB1 receptors are abundant, which is why cannabinoids influence functions such as memory processing, pain regulation and motor control.

CB2 receptors are mainly found on white blood cells, although they are less prevalent than CB1. Stimulation of the CB1 receptor produces cannabis-like effects on body, while no such effect is seen for the CB2 receptor. Thus, CB2 agonists have become subjects of research for potential anti-inflammatory and anti-cancer effects.

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